A Uniform Class of Weak Keys for Universal Hash Functions

In this paper we investigate weak keys of universal hash functions (UHFs) from their combinatorial properties. We find that any UHF has a general class of keys, which makes the combinatorial properties totally disappear, and even compromises the security of the UHF-based schemes, such as the Wegman-Carter scheme, the UHF-then-PRF scheme, etc. By this class of keys, we actually get a general method to search weak-key classes of UHFs, which is able to derive all previous weak-key classes of UHFs found by intuition or experience. Moreover we give a weak-key class of the BRW polynomial function which was once believed to have no weak-key issue, and exploit such weak keys to implement a distinguish attack and a forgery attack against DTC - a BRW-based authentication encryption scheme. Furthermore in Grain-128a, with the linear structure revealed by weak-key classes of its UHF, we can recover any first $(32+b)$ bits of the UHF key, spending no more than $1$ encryption and $(2^{32} + b)$ decryption queries

Related-Key Almost Universal Hash Functions: Definitions, Constructions and Applications

Universal hash functions (UHFs) have been extensively used in the design of cryptographic schemes. If we consider the related-key attack (RKA) against these UHF-based schemes, some of them may not be secure, especially those using the key of UHF as a part of the whole key of scheme, due to the weakness of UHF in the RKA setting. In order to solve the issue, we propose a new concept of related-key almost universal hash function, which is a natural extension to almost universal hash function in the RKA setting. We define related-key almost universal (RKA-AU) hash function and related-key almost XOR universal (RKA-AXU) hash function. However almost all the existing UHFs do not satisfy the new definitions. We construct one fixed-input-length universal hash functions named RH1 and two variable-input-length universal hash functions named RH2, RH3. We show that RH1 and RH2 are both RKA-AXU, and RH3 is RKA-AU for the RKD set $\Phi^\oplus$. Furthermore, RH1, RH2 and RH3 are nearly as efficient as previous similar constructions. RKA-AU (RKA-AXU) hash functions can be used as components in the related-key secure cryptographic schemes. If we replace the universal hash functions in the schemes with our corresponding constructions, the problems about related-key attack can be solved for some RKD sets. More specifically, we give four concrete applications of RKA-AU and RKA-AXU in related-key secure message authentication codes and tweakable block ciphers

Regenerated woody plants influence soil microbial communities in a subtropical forest

10 páginas.- 4 figuras.- 3 tablas.- referencias.- upplementary data to this article can be found online at https://doi. org/10.1016/j.apsoil.2023.104890Forests are critical for supporting multiple ecosystem services such as climate change mitigation. Microbial diversity in soil provides important functions to maintain and regenerate forest ecosystems, and yet a critical knowledge gap remains in identifying the linkage between attributes of regenerated woody plant (RWP) communities and the diversity patterns of soil microbial communities in subtropical plantations. Here, we investigated the changes in soil microbial communities and plant traits in a nine hectare Chinese fir (Cunninghamia lanceolata; CF) plantation to assess how non-planted RWP communities regulate soil bacterial and fungal diversity, and further explore the potential mechanisms that structure their interaction. Our study revealed that soil bacterial richness was positively associated with RWP richness, whereas soil fungal richness was negatively associated with RWP basal area. Meanwhile, RWP richness was positively correlated with ectomycorrhizal (ECM) fungal richness but negatively correlated with the richness of both pathogenic and saprotrophic fungi, suggesting that the RWP-fungal richness relationship was trophic guild-specific. Soil microbial community beta diversity (i.e., dissimilarity in community composition) was strongly coupled with both RWP beta diversity and the heterogeneity of RWP basal area. Our study highlights the importance of community-level RWP plant attributes for the regulation of microbial biodiversity in plantation systems, which should be considered in forest management programs in the future.This work was funded by the National Key Research and Development Program of China (2021YFD2201301 and 2022YFF1303003), the National Natural Science Foundation of China (U22A20612), and the Key Project of Jiangxi Province Natural Science Foundation of China (20224ACB205003).Peer reviewe

Cooperativity among Short Amyloid Stretches in Long Amyloidogenic Sequences

Amyloid fibrillar aggregates of polypeptides are associated with many neurodegenerative diseases. Short peptide segments in protein sequences may trigger aggregation. Identifying these stretches and examining their behavior in longer protein segments is critical for understanding these diseases and obtaining potential therapies. In this study, we combined machine learning and structure-based energy evaluation to examine and predict amyloidogenic segments. Our feature selection method discovered that windows consisting of long amino acid segments of ∼30 residues, instead of the commonly used short hexapeptides, provided the highest accuracy. Weighted contributions of an amino acid at each position in a 27 residue window revealed three cooperative regions of short stretch, resemble the β-strand-turn-β-strand motif in A-βpeptide amyloid and β-solenoid structure of HET-s(218–289) prion (C). Using an in-house energy evaluation algorithm, the interaction energy between two short stretches in long segment is computed and incorporated as an additional feature. The algorithm successfully predicted and classified amyloid segments with an overall accuracy of 75%. Our study revealed that genome-wide amyloid segments are not only dependent on short high propensity stretches, but also on nearby residues

Prediction of Protein Modification Sites of Pyrrolidone Carboxylic Acid Using mRMR Feature Selection and Analysis

Pyrrolidone carboxylic acid (PCA) is formed during a common post-translational modification (PTM) of extracellular and multi-pass membrane proteins. In this study, we developed a new predictor to predict the modification sites of PCA based on maximum relevance minimum redundancy (mRMR) and incremental feature selection (IFS). We incorporated 727 features that belonged to 7 kinds of protein properties to predict the modification sites, including sequence conservation, residual disorder, amino acid factor, secondary structure and solvent accessibility, gain/loss of amino acid during evolution, propensity of amino acid to be conserved at protein-protein interface and protein surface, and deviation of side chain carbon atom number. Among these 727 features, 244 features were selected by mRMR and IFS as the optimized features for the prediction, with which the prediction model achieved a maximum of MCC of 0.7812. Feature analysis showed that all feature types contributed to the modification process. Further site-specific feature analysis showed that the features derived from PCA's surrounding sites contributed more to the determination of PCA sites than other sites. The detailed feature analysis in this paper might provide important clues for understanding the mechanism of the PCA formation and guide relevant experimental validations

Expert Consensus on Microtransplant for Acute Myeloid Leukemia in Elderly Patients -Report From the International Microtransplant Interest Group

Recent studies have shown that microtransplant (MST) could improve outcome of patients with elderly acute myeloid leukemia (EAML). To further standardize the MST therapy and improve outcomes in EAML patients, based on analysis of the literature on MST, especially MST with EAML from January 1st, 2011 to November 30th, 2022, the International Microtransplant Interest Group provides recommendations and considerations for MST in the treatment of EAML. Four major issues related to MST for treating EAML were addressed: therapeutic principle of MST (1), candidates for MST (2), induction chemotherapy regimens (3), and post-remission therapy based on MST (4). Others included donor screening, infusion of donor cells, laboratory examinations, and complications of treatment

The several methods and result comparison of increasing the maximum concentration angle of compound parabolic concentrator (CPC)

This paper simply discusses the structure and the principle of design of compound parabolic concentrator (CPC), introduces three methods of increasing the maximum concentration angle θ max: reflector translation, cutting fundus and reflector revolved, produces the formula of θ max along with the change of geometry size in various methods. To actual CPC with different concentrating ratio, the curve of the maximum concentration increment along with the change of geometry variable in three cases, and analyzes the key factors of affecting the maximum concentration angle of CPC

The complete chloroplast genome of Piptanthus nepalensis, a medicinal plant

Piptanthus nepalensis (Hooker) Sweet is a semi deciduous or deciduous shrub belonging to the genus Piptanthus, Leguminosae. P. nepalensis has been used as a folk medicinal herb in Nepal and was cultivated all over the world as an ornamental plant. In the present study, we sequenced the entire genome of the chloroplast of P. nepalensis. The total length of the chloroplast genome in P. nepalensis is 152,195 bp, including a large single-copy region of 82,048 bp, a small single-copy region of 17,675 bp, and a pair of inverted repeats regions of 26,236 bp. The overall guanine-cytosine (GC) content of the genome was 36.7%. There are 131 genes in the chloroplast genome of P. nepalensis, including 85 protein-coding genes, 8 rRNA genes and 38 tRNA genes. Phylogenetic analysis showed that P. nepalensis is closely related to Maackia floribunda

Theoretical Investigations on Shadow Band Correction Factors for Diffuse Radiation under Isotropic Conditions without Approximation

The precise measurement for irradiance is important for the performance evaluations of solar systems, because both beam and diffuse radiation measurements must be known to calculate the efficiency of a solar system. One of the widely used instruments for diffuse radiation measurement is a pyranometer with a ring. Hence, investigations on shadow band correction factors are necessary. The factors are normally calculated by the expressions of Drummond and Burek et al. under isotropic conditions. However, their calculation results are approximate. While the latitude φ, the inclination angle β and the declination δ are satisfied with the condition of |−tan(φ−β)tanδ|>1, the factors cannot be calculated by their expressions. In this paper, the expressions for the factors under isotropic conditions were obtained by coordinate transformations and discussed in two different coordinate systems without approximation. Our expressions can give precise correction factors in any case and overcome the disadvantages of their expressions. While the sensor is placed horizontally, the maximum relative deviation between the results by the expression in Drummond’s paper and by our expressions is less than 2.3%. When the sensor is placed on a sloped surface, the results by the expressions in Burek’s paper and by our expressions will have considerable differences in some ranges of slope angles and latitudes. The maximum relative deviation is more than 22%